产品货号:
Z22512
中文名称:
P5CS/ALDH18A1抗体
英文名称:
Anti-P5CS/ALDH18A1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-P5CS/ALDH18A1 Antibody |
指标别名 | ALDH18A1;GK;GPR;GSAS;P5CS;PYCS |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,FCM,ELISA |
基因名称 | ALDH18A1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human P5CS/ALDH18A1 recombinant protein (Position:M1-A224). |
实际分子量 | 87KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Delta-1-pyrroline-5-carboxylate synthetase (P5CS) is an enzyme that in humans is encoded by the ALDH18A1 gene.This gene is mapped to 10q24.1.This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities.The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate,a critical step in the de novo biosynthesis of proline,ornithine and arginine.Mutations in this gene lead to hyperammonemia,hypoornithinemia,hypocitrullinemia,hypoargininemia and hypoprolinemia and may be associated with neurodegeneration,cataracts and connective tissue diseases.Alternatively spliced transcript variants,encoding different isoforms,have been described for this gene. |
Uniprot ID | P54886 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | aldehyde dehydrogenase 18 family member A1 |
蛋白名全称 | Delta-1-pyrroline-5-carboxylate synthase |
推荐稀释比 | Western blot(WB) 1:500~2000 Flow cytometry (FCM) 1~3μg/1×106 cells (ELISA): 1:100~1000 |
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